mailer I have had this error when I was messing around with everything. Make sure your HTTP and HTTPS bind are set to the IP of your docker container or VM with Mailcow not the loopback address (127.0.0.1) and the correct HTTP and HTTPS port that you have exposed for Mailcow access.
Make sure NPM is also set to use the IP of the Docker machine or VM you have Mailcow installed on, not the loop address as well as the correct HTTP or HTTPS port you set it to.
Finally, make sure the advanced configure is set to use the actual IP address of the VM or Docket machine not the loop back address.
Like previously stated, donât forget to download and copy the SSL certificate into correct location in your Mailcow folder.
All this has to match!