You need to post the settings map somewhere. You can find it here:
I can try to replicate it with an 1:1 copy of your settings map.
Else: Set debug_modules = ["settings"];
in data/conf/rspamd/override.d/logging.inc
and restart Rspamd. Check and post docker-compose logs --tail=200 -f rspamd-mailcow
logs. The logs must contain the moment the settings map failed.